Who is the strongest Superhero of them all? Usually, people point to Superman. If you include Anime characters, Goku cannot be ignored. And I personally think the Powerpuff Girls are in that category too of characters with no clearly defined limits to their powers, who can seemingly make up abilities at their will to solve a problem.
Oh, but they all fall to the might of Syndrome, the Greatest Superhero... EVER!
Because, how can you fight someone who can stop you from doing anything whenever he wants? You can't.
First time I can recall ever drawing Superman and Goku, and I know this is the first time drawing Syndrome. I think they turned out pretty well. Had quite a bit of Powerpuff Girls drawing experience, and it's not that complex of a style.
Syndrome is from The Incredibles.
Blossom is from The Powerpuff Girls.
Superman is from... uh... Superman.
Goku is from Dragon Ball.